The NeuroQuant normative database provides a crucial reference for interpreting brain MRI volumetric measurements in a clinical context. By comparing an individual patient’s brain structure volumes to an age- and gender-matched healthy population, clinicians can determine whether a volume is within normal ranges or indicative of potential neurodegenerative change. This white paper outlines an updated model for the NeuroQuant normative database, employing a more advanced statistical fitting method to better capture age-related changes in brain volume distributions.
